Arthur (1996)

Creator: Marc Brown
Air Dates: September 2nd, 1996 - Present
Seasons: 21 (19 aired)
Episodes: 239 (217 aired)
(source)

Arthur is a cartoon based a series of children's books written by Marc Brown. It's an educational television series that airs on PBS. Yes, I know it's a children's show, but I don't care! I loved this show as a kid, and it's great. This was one of my favorite children's shows when I was little (along with Blues Clues and Barney (Shut up! Barney was awesome,)

My Little Pony: Friendship is Magic (2010)

Creator(s): Lauren Faust/Hasbro, Inc.
Air Dates: October 10, 2010
Seasons: 6
Episodes: 119 (plus 24 more to come)
(no source since I know this stuff off the top of my head)

My Little Pony: Friendship is Magic is a part of the fourth generation of the My Little Pony franchise. With the success of the Transformers movies, Hasbro wanted to revamp some of their other properties. So, Lauren Faust was hired to develop the new My Little Pony cartoon.